Net Effects: Price Reductions

Collectively, these policy changes serve to combat the growing bubble that has expanded between insulin list prices and net prices, driven by the rebates and discounts privately negotiated between insulin manufacturers and the health insurance/PBM industry.

Manufacturers are behooved to enact price reductions to avoid triggering monumental rebates, such as the Medicaid rebates that could outweigh net sales for insulins sold to Medicaid beneficiaries in 2024.

Current and Anticipated Insulin Price Reductions

Eli Lilly

Insulin
Active/Anticipated Price Change
Humalog® (insulin lispro)
70% Manufacturer price discount, effective Q4 2023
Humulin® (insulin human)
70% Manufacturer price discount, effective Q4 2023
Insulin Lispro
70% Manufacturer price discount, effective Q2 2023
Rezvoglar™ (insulin glargine-aglr)
78% Manufacturer discount versus biosimilar Lantus®, effective Q2 2023

Novo Nordisk

Insulin
Active/Anticipated Price Change
Levemir® (insulin detemir)
65% Manufacturer price discount, effective Q1 2024
Novolin® (insulin human)
65% Manufacturer price discount, effective Q1 2024
Novolog® (insulin aspart)
75% Manufacturer price discount, effective Q1 2024
Novolog® Mix 70/30 (insulin aspart protamine/insulin aspart)
75% Manufacturer price discount, effective Q1 2024
Insulin Aspart (unbranded Novolog®)
50% Manufacturer price discount to match list price of respective branded insulin (Novolog®)

Insulin Aspart Protamine/ Insulin Aspart (unbranded NovoLog® Mix 70/30)

50% Manufacturer price discount to match list price of respective branded insulin (Novolog® Mix 70/30)

Insulin Degludec (Unbranded Tresiba®)

65% Manufacturer discount versus biosimilar Tresiba®

Sanofi

Insulin
Active/Anticipated Price Change
Apidra® (insulin glulisine)
70% Manufacturer price discount; effective Q1 2024
Lantus® (insulin glargine)
78% Manufacturer price discount effective Q1 2024

The rationale driving these insulin price cuts is likely multifactorial – a combination of the aforementioned reasons of appeasing the masses, garnering public goodwill, complying with IRA stipulations, and avoiding potentially disastrously high Medicaid rebates per the 2024 policy update removing rebate caps.

Policy Reforms

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Product Discontinuations

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