Recognizing Polypharmacy & Next Steps

Due to the dangers of polypharmacy, it is important that communities stay alert to the signs.

There are three primary considerations to recognizing polypharmacy: new medication, new side effect, and new symptom. When a resident starts a new medication, be sure to watch for things like:

  • A change in participation in daily activities
  • Falls
  • A change in behavior (e.g. depression, anxiety, or delirium)
  • Symptoms like nausea, headache, stomach pain, or rash

If nursing staff suspects polypharmacy, next steps include:

  • Ask if a new medication was recently started.
  • Develop a list of current medications found in bottles, lists, and pillboxes. Include over-the-counter medications and vitamins and supplements. Check for both the date of the last fill and the expiration date.
  • Request an on-demand review of the resident’s medication regimen by the team pharmacist. The main purpose of a review is to improve the appropriateness of medications, reduce harm, and enhance outcomes.


39% of seniors over age 65 take five or more medications.


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